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KMID : 1151720190080020023
Journal of Korean Society of Cognitive Rehabilitation
2019 Volume.8 No. 2 p.23 ~ p.41
Effects of Spatial Cognitive Training based on Virtual Reality on Prefrontal Cortex of Older Adults with Mild Cognitive Impairment: Single Subject Design
Park Jin-Hyuck

Abstract
Objective: This study was aimed at investigating effects of spatial cognitive training based on virtual reality on prefrontal cortex activation of the elderly with mild cognitive impairment(MCI).

Methods: A single-subject study method using multiple baselines across individuals was implemented in this study. 3 older adults with MCI performed a total of 20 sessions with different baseline and intervention periods for 45 minutes a session. After each session, activation in prefrontal cortex was measured by using functional near-infrared spectroscopy and performance on the spatial cognitive training was observed. Episodic memory was also evaluated at pre- and post-test.

Result: All participants showed a significant increase in activation in prefrontal cortex and improvement in performance on the spatial cognitive training. Specifically, the activation(¥ì M/mm) was increased from 1.562 to 3.699 in subject 1, from 1.073 to 2.380 in subject 2, and from 1.322 to 3.360 in subject 3. Distance error(mm) from the spatial cognitive training was decreased from 75.92 to 60.39 in subject 1, from 67.87 to 50.56 in subject 2, and from 63.73 to 58.96 in subject 3. In addition, episodic memory was improved at post-test except for subject 2.

Conclusion: These results suggested that the spatial cognitive training based on virtual reality would be useful in increasing in activation in prefrontal cortex and improving spatial cognition of older adults with MCI, which might have a positive effect on improving in episodic memory.
KEYWORD
Episodic memory, Functional near-infrared spectroscopy, Mild cognitive impairment, Prefrontal cortex, Spatial cognition
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